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Session 2 - ATRT
Thursday, May 7, 9:25am - 10:15am

MODERATORS: Soumen Khatua, Brian Rood

PM-02 Conditional inactivation of Smarcb1 in P0 permissive mouse cells generates rhabdoid tumors in the peripheral nervous system and in the brain
Jeremie Vitte*1, Fabrice Chareyre1, Anat Stemmer-Rachamimov2, Alexander Judkins3, Marco Giovannini1
1Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, USA, 2Molecular Neuro-Oncology and Pathology Department, Massachusetts General Hospital and Harvard Medical School, USA, 3Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, USA
AT-04 Targeting Myc driven transcriptional output in atypical teratoid rhabdoid tumor
Irina Alimova*, Sujatha Venkataraman, Angela Pierce, Andrea Greisinger, Diane Birks, Ilango Balakrishnan, Nicholas Foreman, Rajeev Vibhakar
University of Colorado SOM, USA
AT-05 Targeting mTOR downstream of LIN28 in Atypical Teratoid Rhabdoid Tumors promotes apoptosis and suppresses tumorigenicity
Jeffrey Rubens*, Antoinette Price, Charles Eberhart, Eric Raabe
Johns Hopkins Hospital, USA
AT-01 Therapeutic targeting of INI1 deficiency in pediatric ATRT: a pre-clinical study utilizing patient derived orthotopic xenograft (PDOX) models
Holly Lindsay*1, Mari Kogiso1, Lin Qi1, Jeffrey Murray2, Laszlo Perlaky1, Jack Su1, Patricia Baxter1, Adekunle Adesina1, Donald Parsons1, Murali Chintagumpala1, Xiao-Nan Li1
1Baylor College of Medicine, USA, 2Cook Children's Hospital, USA
AT-07 Successful treatment of ATRT patients without adjuvant radiation: a multi institutional Canadian experience
Dennis Ku*1, Lucie Lafay-Cousin3, Chris Fryer2, Juliette Hukin2, Doug Strother3, Annie Huang1, Eric Bouffet1
1The Hospital for Sick Children, Canada, 2BC Children Hospital, Canada, 3Alberta Children's Hospital, Canada