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SESSION 8: Update on International Clinical Trials in Meningioma
Saturday, June 18, 2016, 1:15pm - 2:45pm

 

Moderators: James Perry, David Reardon

 

Panel Discussion: Michael Jenkinson, James Perry, David Reardon, Eva Galanis, Ghazeleh Tabatabai


Intermediate-risk meningioma: Initial outcomes from NRG Oncology/RTOG-0539
Leland Rogers*1, Peixin Zhang2, Michael Vogelbaum3, Arie Perry4, Lynn Ashby5, Jignesh Modi6, Anthony Alleman7, James Galvin8, David Brachman5, Joseph Jenrette9, John de Groot10, Joseph Bovi11, Maria Werner-Wasik12, Jonathan Knisely13, Minesh Mehta14
1Virginia Commonwealth University, USA, 2NRG Oncology, USA, 3Cleveland Clinic, USA, 4University of California, San Francisco, USA, 5Barrow Neurological Institute, USA, 6Yale University, USA, 7University of Oklahoma, USA, 8IROC Philadelphia RT, USA, 9Medical University of South Carolina, USA, 10MD Anderson Cancer Center, USA, 11Medical College of Wisconsin, USA, 12Thomas Jefferson University, USA, 13Hofstra North Shore-LIJ School of Medicine,, USA, 14University of Maryland, USA
1:15pm
Development of clinical precision medicine approaches in meningiomas
Priscilla Brastianos*1, Qian Shi2, Sandro Santagata3, Keith Anderson2, Suriya Jeyapalan4, Dan Cahill1, Elise Horvath5, Fred Barker1, Evanthia Galanis6
1Massachusetts General Hospital Cancer Center, USA, 2Alliance Statistics and Data Center, Mayo Clinic, USA, 3Brigham and Women's Hospital, Harvard Medical School, USA, 4Tufts University, USA, 5Alliance Protocol Operations Office, USA, 6Mayo Clinic, -
1:30pm
A single arm, open-label phase II study of Nivolumab in adult participants with recurrent high-grade meningioma
Ian Dunn*1, Sandro Santagata1, Rameen Beroukhim1, Lakshmi Nayak1, Eudocia Quant-Lee1, Andrew Norden1, Mikael Rinne1, Priscilla Brastianos2, Sarah Gaffey1, Patrick Wen1, David Reardon1
1Dana-Farber/Brigham and Women's Hospital, USA, 2Massachusetts General Hospital, USA
1:40pm
The ROAM / EORTC 1308 trial: Radiation versus Observation following surgical resection of atypical meningioma: a randomised controlled trial – study update
Michael Jenkinson*1,2, Mohsen Javadpour3, Brian Haylock4, Bridget Young1, Helen Hind1, Jacqui Vinten2, Helen Bulbeck8, Kumar Das2, Michael Farrell3, Seamus Looby3, Helen Hickey1, Matthias Preusser5, Conor Mallucci1, Dyfrig Hughes6, Carroll Gamble1, Damien Weber7
1University of Liverpool, UK, 2The Walton Centre NHS Foundation Trust, UK, 3Beaumont Hospital, Ireland, 4Clatterbridge Cancer Centre, UK, 5Comprehensive Cancer Center, Austria, 6Bangor University, UK, 7Centre for Proton Therapy, Paul Scherrer Institute, Switzerland, 8brainstrust charity, UK
1:50pm
Prospective trial of surgery and permanent intraoperative brachytherapy (S+BT) using a modular, biocompatable radiation implant for recurrent aggressive meningiomas
David Brachman*1,2, Christopher Dardis1,3, Peter Nakaji1,2, Emad Youssef1,2, Theresa Thomas3,2, Kris Smith1, Nader Sanai1, Stephen Sorensen3
1Barrow Neurological Institute, USA, 2GammaTile, LLC, USA, 3St Josephs Hospital/Dignity Health, USA
2:00pm
Challenges in the design of clinical trials investigating targeted therapy in meningiomas
Mariza Daras, Ingo Mellinghoff, Thomas Kaley*
Memorial Sloan Kettering Cancer Center, USA
2:10pm