conference logo
 
Programme  Titles  Presenters  Topics 
Presenter Index

Aguilar-Ortiz, Marco R.
National Institute of Pediatrics (INP), Mexico
Primary central nervous system non hodgkin lymphoma in a pediatric patient without immunodeficiency related. case report and literature review
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Alimova, Irina
University of Colorado SOM, USA
Targeting Myc driven transcriptional output in atypical teratoid rhabdoid tumor
Thursday, May 7:  Session 2 - ATRT  -  9:25am - 10:15am
 

Amani, Vladimir
University of Colorado Anschutz Medical Campus, USA
PLK1 as a potential therapeutic target for DIPG
Thursday, May 7:  Session 3 - Brainstem Gliomas/High Grade Gliomas  -  10:35am - 12:05pm
 

Bakhshinyan, David
McMaster University, Canada
Discovering the treatment refractory BTIC population in group 3 medulloblastoma
Friday, May 8:  Session 9 - Medulloblastoma II  -  9:00am - 10:10am
 

Bielamowicz, Kevin
Baylor College of Medicine, USA
Multispecific CAR T cells for the treatment of high grade glioma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Bie, Li
The First Hospital of Jilin University, China
4EBP1 participates in cisplatin resistance of human glioma cells through PI3K/AKT/mTOR pathway
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
MGMT promoter methylation status and miRNA-181 family expression as prognostic markers in glioblastoma patients
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Bouffet, Eric
The Hospital for Sick Children, Canada
Very encouraging long-term survival and neurocognitive outcome of young children treated for medulloblastoma with sequential high dose chemotherapy
Friday, May 8:  Session 9 - Medulloblastoma II  -  9:00am - 10:10am
 

Brabetz, Sebastian
Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Germany
Establishment and molecular characterization of patient-derived xenograft models of pediatric brain tumors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Breunig, Joshua
Cedars-Sinai, USA
A piggyBac toolkit for rapid testing of putative pediatric GBM driver genes with extensions for investigating cells of recurrence
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
Effects of T-cell TGF-β signaling abrogation on survival in pediatric glioma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
Mosaic genetic progression models of low grade pediatric brain tumors reveal unique features of tumor evolution
Thursday, May 7:  Session 5 - Low Grade Glioma  -  2:15pm - 3:15pm
 

Brugmann, William
University of Texas M.D. Anderson Cancer Center, USA
NK cell immunotherapy for pediatric brain tumors: overcoming resistance to expand therapeutic success
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Campbell, Brittany B.
Program in Genetics and Genome Biology, The Hospital for Sick Children, Canada
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated malignant brain tumors in children
Thursday, May 7:  Session 1 - Featured Abstract Presentations  -  8:25am - 9:25am
 

Carvalho, Diana
Institute of Cancer Research, UK
Infantile glioblastoma with sarcomatous histology driven by ETV6:NTRK3 fusions are sensitive to Trk inhibition by PHA-848125
Thursday, May 7:  Featured Poster Discussion: 5:30pm - 6:10pm
 

Castellino, Robert
Aflac Cancer and Blood Disorders Center, USA
WIP1 augments sonic hedgehog (SHH) signaling and is a target in SHH medulloblastomas
Friday, May 8:  Session 10 - Medulloblastoma II, Part 2  -  10:30am - 11:20am
 

Chalmers, Zachary R
Foundation Medicine Inc, USA
Comprehensive genomic profiling (CGP) of pediatric gliomas reveals a high frequency of clinically relevant genomic alterations (CRGA) associated with benefit from targeted therapy
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Cigna*, Sara Maria
Institut Curie, France
Post-translational regulation of Atoh1: from cerebellar development to medulloblastoma formation
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Da Ros, Martina
Neuro-oncology Unit, Department of Paediatric Medicine, Anna Meyer Children's University Hospital, Italy
Pharmacological modulation of blood-brain barrier: a novel therapeutic approach to refractory CNS tumors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Dey, Abhinav
Emory University, USA
Sonic hedgehog induces YB-1 in a YAP-dependent manner to regulate Igf2 expression and proliferation in cerebellar granule neuron progenitors and medulloblastoma cells
Friday, May 8:  Session 10 - Medulloblastoma II, Part 2  -  10:30am - 11:20am
 

Dobson, Tara
University of Texas MD Anderson Cancer Center, USA
Dissecting the role of epigenetic modulators in Shh-driven medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Dombrowski, Stephen
Department of Neurological Surgery, Pediatric Neurosurgical Oncology, Cleveland Clinic, USA
Inhibition of epigenetic regulation as a therapy for pediatric high grade glioma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Donson, Andrew
UCDenver, USA
Anti-tumor effect of trastuzumab, GM-CSF and IL-2 combinatorial therapy in pediatric ependymoma
Friday, May 8:  Session 8 - Ependymoma  -  8:20am - 9:00am
 

DUMOUCEL, Sophie
CHU Ste Justine, Canada
Personalized targeted therapy in refractory or relapsed cancer in childhood (Triceps Study)
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Eisenstat, David
University of Alberta, Canada
DLX homeobox genes regulate neuronal vs oligodendroglial cell fate decisions: potential relevance to pediatric glioneuronal tumors and high grade gliomas
Thursday, May 7:  Session 3 - Brainstem Gliomas/High Grade Gliomas  -  10:35am - 12:05pm
 

Entz-Werlé, Natacha
EA3430, University of Strasbourg, France
Hypoxia pathway driven by HIF-1alpha are predominantly involved in pediatric high grade glioma and represent promising therapeutic targets
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
Pediatric grade II glioma molecular screening in adolescents and young adults
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Erdreich-Epstein, Anat
Children's Hospital Los Angeles, USA
PID1 is a chemotherapy sensitizer and candidate tumor suppressor in medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Erker, Craig
Medical College of Wisconsin, USA
When to biopsy a pineal region mass in children
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Farassati, Faris
The University of Kansas Medical School, USA
RalA in biology and therapy of MPNST in correlation to cancer stem cells
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Feldman, Michael
Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, USA
Induced cisplatin resistance in medulloblastomas
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Finlay, Jonathan
Nationwide Children's Hospital and The Ohio State University, USA
Preliminary results of a feasibility pilot study of “Gempox” (gemcitabine, oxaliplatin, and paclitaxel) in pediatric and adult patients with refractory or recurrent central nervous system (CNS) germ cell tumors (GCT): the International CNS GCT Consortium Trial, CNS GCT- 4
Thursday, May 7:  Session 6 - Germ Cell Tumors/Choroid Plexus Tumors  -  3:40pm - 4:40pm
 

Flores, Catherine
University of Florida, USA
Anti-tumor efficacy of adoptive cellular therapy is significantly increased by hematopoietic stem cells
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Fons, Nathan
Experimental Pathology, Yale University, USA
Development of a novel gene targeting and clone screening platform to engineer common pediatric glioma mutations into model cell lines
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Foreman, Bronwen
University of Colorado, Anschutz Medical Campus, USA
Targeting medulloblastoma with a new small-molecule drug that inhibits MYC mediated translation
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Friedman, Gregory
The University of Alabama at Birmingham, USA
Tumor location remodels transcriptomic profiles in a pediatric medulloblastoma xenograft
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Fukuoka, Kohei
Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Japan
Molecular classification of ependymomas in  a Japanese cohort
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Gholamin, Sharareh
Stanford , Institute of Stem Cell Biology and Regenerative Medicine, USA
A humanized co-transplant xenograft mouse model, to study toxicity of drugs targeted against pediatric brain tumors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Giannios, John
Int Soc of Molecular and Genomic Medicine and Int Assoc of Perioperative Medicine and Nanosurgery, Greece
GBM-associated exosome-pulsed autologous DC vaccine (DC-Vex®) induces D-2 apoptotic-stage and bystander killing-effect in GBM of the mesenchymal type
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
Immunotargeted-molecular-robotic-nanosurgery(ITMRN) eradicates GBM stem-cells with radiofrequency dielectric heating(RFDH) mediated via silver-immunonanobots linked with anti-CD133 MAbs
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Griesinger, Andrea
University of Colorado Denver, Anschutz Medical Campus, USA
Activation of the IL6/STAT3 pathway in childhood ependymoma is associated with a pro-inflammatory tumor microenvironment and a poor prognosis
Friday, May 8:  Session 8 - Ependymoma  -  8:20am - 9:00am
 
Inflammation driver, NF-kB, is associated with poor outcome Group A ependymoma and regulates a key immune suppressive signaling pathway involved in the tumor microenvironment
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Gump, William
Kosair Children's Hospital, USA
Challenges in the management of hypothalamic juvenile pilocytic astrocytoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
Primary Ewing sarcoma of the scalp with apparent epidural extension: case illustration
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Gupta, Nalin
University of California San Francisco, USA
Characterization of infiltrating myeloid cells associated with xenografted gliomas in the rodent brain
Thursday, May 7:  Featured Poster Discussion: 5:30pm - 6:10pm
 

Hanaford, Allison
Johns Hopkins School of Medicine, USA
Pathway analysis of a human neural stem cell model of aggressive medulloblastoma reveals CDK inhibition as a potential therapeutic modality
Friday, May 8:  Session 9 - Medulloblastoma II  -  9:00am - 10:10am
 

Hashizume, Rintaro
Northwestern University, USA
Targeted inhbition of histone demethylase activity for the treatment of pediatric brainstem gliomas
Thursday, May 7:  Session 3 - Brainstem Gliomas/High Grade Gliomas  -  10:35am - 12:05pm
 

Hatcher, Rashieda
Children's Cancer Hospital and UT MD Anderson Cancer Center, USA
Study of epigenetic deregulation of a novel deubiquitylase in medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Henderson, Jacob
Doernbecher Children's Hospital OHSU, USA
Evaluating the oncogenic potential of TSC1/2 mutations and efficacy of MTOR inhibitors in high risk pediatric medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Hoffman, Lindsey M.
Cincinnati Children's Hospital Medical Center, USA
A feasibility and randomized phase II study of vorinostat, bevacizumab, or temozolomide during radiation followed by maintenance chemotherapy in newly-diagnosed pediatric high-grade glioma: Children’s Oncology Group study ACNS0822
Thursday, May 7:  Session 4 - High Grade Glioma  -  1:15pm - 2:25pm
 
Clinical, radiographic, and histologic characteristics of long-term survivors of diffuse intrinsic pontine glioma: a report from The International DIPG Registry
Thursday, May 7:  Session 3 - Brainstem Gliomas/High Grade Gliomas  -  10:35am - 12:05pm
 

Hong, Christopher
National Institute of Neurological Disorders and Stroke, Surgical Neurology Branch, USA
IDH1-mutated pituitary adenoma challenges traditional characterization of Maffucci syndrome
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Ho, Sze Chun Winson
National Institute of Health, USA
LB100, a novel protein phosphatase 2A inhibitor, enhances cisplatin and radiation mediated cytotoxicity and overcome cisplatin resistance in-vitro
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Hovestadt, Volker
Division of Molecular Genetics, German Cancer Research Center (DKFZ), Germany
DNA methylation in medulloblastoma and molecular diagnostics of brain tumors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Ichimura, Koichi
Division of Brain Tumor Translational Research, National Cancer Center Research Institue, Japan
Elucidation of pathogenesis in intracranial germ cell tumors based on a genome-wide methylation study
Thursday, May 7:  Session 6 - Germ Cell Tumors/Choroid Plexus Tumors  -  3:40pm - 4:40pm
 

Imber, Brandon
Department of Radiation Oncology, University of California, San Francisco, USA
Intracranial nongerminomatous germ cell tumors: treatment strategies and outcomes
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Jackson, Sadhana
Johns Hopkins, USA
The effect of regadenoson-induced transient disruption of the blood brain barrier on temozolomide delivery to rat brain parenchyma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Jain, Payal
Department of Neurosurgery, University of Pennyslvania Perelman School of Medicine, The Children's Hospital of Philadelphia, USA
Combinatorial pathway targeting approaches for BRAF-fusions associated with pediatric low-grade gliomas
Thursday, May 7:  Session 5 - Low Grade Glioma  -  2:15pm - 3:15pm
 

Kahn, Suzana
Neurosurgery Department, Stanford University, USA
Notch1 promotes MYC medulloblastoma metastasis, initiation and maintenance
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Kankean, Anne
University of New South Wales, Australia
The anti-apoptotic protein ARC is over-expressed in malignant glioma and correlates with patient outcome
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
Trilexium inhibits the expression of t-NOX and is a novel, potentially potent therapy for Diffuse Intrinsic Pontine Gliomas
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Kaur, Harpreet
The Johns Hopkins Hospital, USA
Disrupting the epigenetic modifier HMGA2 in DIPG and GBM inhibits tumor invasion, growth and tumorigenicity
Thursday, May 7:  Session 4 - High Grade Glioma  -  1:15pm - 2:25pm
 

Kaur, Ravinder
Regenerative Medicine Program, Department of Biochemistry and Medical Genetics and Physiology, University of Manitoba, Canada
Neural derivatives from human embryonic stem cells: a cellular system to study the role of Otx2 in medulloblastoma progression.
Friday, May 8:  Session 9 - Medulloblastoma II  -  9:00am - 10:10am
 

Kelly, Teresa
Children's Hospital of Wisconsin, USA
Effectiveness of perfusion and diffusion imaging for grading pediatric brain tumors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Kievit, Forrest
University of Washington, USA
Nanoparticle siRNA delivery vehicles inhibit DNA repair and sensitize pediatric brain tumor cells to radiation therapy
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Kimura, Kyle
The University of Kansas School of Medicine, USA
Ezh2, a novel target in treatment of medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Kondo, Akihide
Juntendo University, Japan
Prognostic impact of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Kool, Marcel
German Cancer Research Center, Germany
Atypical Teratoid/Rhabdoid Tumour is a genetically homogeneous but epigenetically heterogeneous disease that is defined by subgroup specific super-enhancers
Thursday, May 7:  Session 1 - Featured Abstract Presentations  -  8:25am - 9:25am
 
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades and age groups
Friday, May 8:  Session 8 - Ependymoma  -  8:20am - 9:00am
 
Molecular (re-)classification of CNS-primitive neuroectodermal tumors
Thursday, May 7:  Session 7 - Medulloblastoma 1  -  4:40pm - 5:10pm
 

Koschmann, Carl
University of Michigan, USA
ATRX loss promotes tumor growth and impairs genetic stability in glioblastoma
Thursday, May 7:  Session 4 - High Grade Glioma  -  1:15pm - 2:25pm
 

Krenciute, Giedre
Baylor College of Medicine, USA
A scFv-based CAR to redirect T cells to IL13Rα2-positive pediatric glioma
Thursday, May 7:  Session 4 - High Grade Glioma  -  1:15pm - 2:25pm
 

Krishnatry, Rahul
The Hospital for Sick children, Canada
Radiation therapy is associated with increased late mortality in long-term adult survivors of childhood low grade glioma: A population based study
Thursday, May 7:  Featured Poster Discussion: 5:30pm - 6:10pm
 

Ku, Dennis
The Hospital for Sick Children, Canada
Successful treatment of ATRT patients without adjuvant radiation: a multi institutional Canadian experience
Thursday, May 7:  Session 2 - ATRT  -  9:25am - 10:15am
 

Kundu, Palak
Stanford University School of Medicine, USA
Boost volume effects on incidental hippocampal dose in pediatric medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Larson, Jon
St. Jude Children's Research Hospital, USA
Biological consequences of histone mutations in the mammalian brain
Thursday, May 7:  Session 4 - High Grade Glioma  -  1:15pm - 2:25pm
 

Leary, Sarah
Seattle Children's, USA
Feasibility of vorinostat combined with isotretinoin and chemotherapy for young children with newly diagnosed embryonal brain tumors: A Pediatric Brain Tumor Consortium Study
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
Targeted next generation sequencing in malignant supratentorial pediatric brain tumors reveals actionable mutations
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Lee, Catherine
Sanford Burnham Medical Research Institute (SBMRI), USA
Regulation of medulloblastoma formation by Gfi1 and Gfi1b
Friday, May 8:  Session 10 - Medulloblastoma II, Part 2  -  10:30am - 11:20am
 

Leon, Jose
Instituto Nacional de Pediatria, Mexico
Multicentric primary central nervous system diffuse large b cell lymphoma in an inmunocompetent adolescent, case report
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Leprivier, Gabriel
British Columbia Cancer Research Centre and University of British Columbia, Canada
The eEF2 kinase, a mediator of medulloblastoma adaptation to metabolic stress, supports fatty acid oxidation
Friday, May 8:  Session 9 - Medulloblastoma II  -  9:00am - 10:10am
 

Liang, Lisa
University of Manitoba, Canada
Functional characterization of novel biomarkers in selecting for subtype specific medulloblastoma phenotypes
Thursday, May 7:  Featured Poster Discussion: 5:30pm - 6:10pm
 

Lindberg, Olle R
University of California, San Francisco (UCSF), USA
Modeling pediatric GBM using neural stem cell-derived tumors with divergent behavior
Thursday, May 7:  Session 3 - Brainstem Gliomas/High Grade Gliomas  -  10:35am - 12:05pm
 

Lindsay, Holly
Baylor College of Medicine, USA
Therapeutic targeting of INI1 deficiency in pediatric ATRT: a pre-clinical study utilizing patient derived orthotopic xenograft (PDOX) models
Thursday, May 7:  Session 2 - ATRT  -  9:25am - 10:15am
 

Lin, Frank Y.
Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, USA
Identification of targetable mutations in rare pediatric brain tumors by clinical whole exome sequencing
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Liu, Kun-Wei
Sanford-Burnham Medical Research Institute, USA
HDAC and PI3K antagonists cooperate to inhibit growth of MYC-driven medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Li, Xiao-Nan
Texas Children's Cancer Center, Baylor College of Medicine, USA
Autopsy derived orthotopic xenograft (ADOX) mouse models for terminal pediatric brain tumors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
Oncolytic picornavirus SVV-001 prolongs animal survival in a patient tumor-derived orthotopic xenograft mouse model of Group 3 supratentorial primitive neuroectodermal tumor
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Lucchesi, Maurizio
Neuro-oncology Unit, Department of Paediatric Medicine, Meyer Children's University Hospital, Italy
Pediatric anaplastic meningioma: a case report successfully treated with combined chemotherapy for soft tissue sarcomas and radiotherapy.
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Lulla, Rishi
Division of Hematology, Oncology, Neuro-Oncology and Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg School of Medicine, USA
MicroRNA expression patterns in tissue and cerebrospinal fluid aid in molecular classification of pediatric medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Lu, Richard
Cincinnati Children's Hospital Medical Center, USA
The critical role of Olig2-expressing progenitors in the initiation of G-protein mediated Sonic Hedgehog-driven medulloblastoma
Thursday, May 7:  Featured Poster Discussion: 5:30pm - 6:10pm
 

Mackay, Alan
Institute of Cancer Research, UK
Integrative molecular meta-analysis of 700 pediatric high grade glioma and DIPG defines widespread inter- and intra-tumoral heterogeneity
Thursday, May 7:  Session 4 - High Grade Glioma  -  1:15pm - 2:25pm
 

Mallory, Samantha
University of Oklahoma Health Science Center, USA
OKN-007: a novel compound for treating pediatric glioblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Manoranjan, Branavan
McMaster Stem Cell & Cancer Research Institute, McMaster University, Canada
Activated Wnt signaling targets Sox2+ treatment-refractory Shh-dependent medulloblastoma stem cells
Thursday, May 7:  Featured Poster Discussion: 5:30pm - 6:10pm
 

Margol, Ashley
Children's Hospital Los Angeles, USA
Molecular subgroups of medulloblastoma identification using non-invasive magnetic resonance spectroscopy
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Martinez-Velez, Naiara
Clinica Universidad de Navarra, Spain
Delta-24-RDG as an alternative therapeutic tool for pHGG/DIPG
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Mistry, Matthew
The Hospital for Sick Children, Canada
BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma
Thursday, May 7:  Session 5 - Low Grade Glioma  -  2:15pm - 3:15pm
 

Mitchell, Duane
University of Florida, USA
RNA nanoparticle vaccines re-program host immunity in favor of enhanced effector responses against intracranial malignancies
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Modzelewska, Katarzyna
Huntsman Cancer Institute, USA
Using a zebrafish pediatric brain tumor model for pre-clinical drug screening
Thursday, May 7:  Featured Poster Discussion: 5:30pm - 6:10pm
 

Monje, Michelle
Stanford University, USA
Neuronal activity-regulated secretion of neuroligin-3 promotes glioma growth
Thursday, May 7:  Session 1 - Featured Abstract Presentations  -  8:25am - 9:25am
 

Mueller, Sabine
University of California San Francisco, USA
Effects of TORC1/2 inhibitor MLN0128 alone and in combination with MEK inhibition in BRAF mutated glioma cells
Thursday, May 7:  Session 5 - Low Grade Glioma  -  2:15pm - 3:15pm
 

Mulcahy Levy, Jean M.
University of Colorado Anschutz Medical Campus, USA
Autophagy inhibition reverses resistance to targeted BRAF therapy in pediatric CNS tumors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Nazarian, Javad
Children's National Medical Center, USA
A standardized autopsy procurement allows for the comprehensive study of DIPG biology
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Neuwelt, Edward
Oregon Health & Science University, USA
Use of IV N-acetylcysteine in combination with sodium thiosulfate for prevention of ototoxicity in pediatric patients
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Ng, Ho-Keung
Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong
Expression of CRMP1 inhibits cell proliferation of medulloblastoma and is regulated by HMGA1
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Nunez, Felipe J.
University of Michigan, USA
A novel mouse model of young adult glioblastoma: In vivo expression of mutated IDH1 (R132H) gene using the Sleeping Beauty Transposase System
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Ocasio, Jennifer
University of North Carolina, USA
GSK-3 promotes proliferation during postnatal cerebellar development and may be targeted in medulloblastoma therapy
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Olow, Aleksandra K.
University of California, USA
Targeted combinatorial approach for treatment of pediatric low grade gliomas in the context of BRAFV600E and KIAA1549:BRAF mutations
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Osorio-Alamillo, Yahiel
Instituto Nacional de Pediatria Oncology Department, Mexico
Primary central nervous system melanocytic lesions in childhood: experience at National Institute of Pediatrics in Mexico
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Osorio, Diana
NYU Langone Medical Center, USA
Effects of everolimus on meningioma growth in patients with neurofibromatosis Type 2
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Panigrahy, Ashok
Childrens Hospital of Pittsburgh, USA
Serial metabolism of diffuse intrinsic pontine glioma treated with peptide based vaccine therapy
Thursday, May 7:  Session 3 - Brainstem Gliomas/High Grade Gliomas  -  10:35am - 12:05pm
 

Park, Ilwoo
Surbeck Laboratory of Advanced Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco,, USA
Measuring tumor metabolism in diffuse intrinsic pontine gliomas (DIPG) using hyperpolarized carbon-13 MR spectroscopic imaging
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Peacock, John
The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Laboratory Medicine and Pathobiology, University of Toronto, Canada
An animal model of 17p deletion in medulloblastoma
Friday, May 8:  Session 9 - Medulloblastoma II  -  9:00am - 10:10am
 

Perez, Augustus
University of MIssissippi Medical Center, USA
Metachronous supratentorial intracranial malignant tumors in two pediatric patients with infratentorial medulloblastoma on hormone therapy
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Pham, Christina
University of Florida, USA
Immunologic targeting of medulloblastoma subtypes using developmentally regulated antigens
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Phoenix, Timothy
St. Jude Children's Research Hospital, USA
Medulloblastoma subtypes specify inter-tumoral vascular blood brain barrier heterogeneity
Thursday, May 7:  Session 7 - Medulloblastoma 1  -  4:40pm - 5:10pm
 

Piazza, Martin
National Institute of Neurological Disorders and Stroke, Surgical Neurology Branch, USA
Disruption of perivascular astrocytic foot processes characterizes MRI enhancement in pediatric brain tumors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Pietsch, Torsten
Department of Neuropathology & Brain Tumor Reference Center, University of Bonn, Germany
CNS germinomas are characterized by global demethylation, chromosomal instability and mutational activation of the Kit-, Ras/Raf/Erk- and Akt-pathways
Thursday, May 7:  Session 6 - Germ Cell Tumors/Choroid Plexus Tumors  -  3:40pm - 4:40pm
 
Genome-wide copy number analysis, neuropathological classification and analysis of hedgehog activation: Histology reflects genetics and biology in medulloblastomas of young children
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 
Implementation of next generation copy number and mutational analysis in routine neuropathology: molecular inversion profiling is a helpful tool in differential diagnostics and prognostification of pediatric brain tumors
Thursday, May 7:  Session 6 - Germ Cell Tumors/Choroid Plexus Tumors  -  3:40pm - 4:40pm
 

Potts, Chad
Emory University, USA
A role for NADPH oxidase 4-generated reactive oxygen species in Sonic hedgehog-driven proliferation of cerebellar granule neuron precursors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Pouponnot, Celio
Institut Curie/ CNRS UMR3347 / INSERM U1021, France
Aggressive medulloblastoma subverts the photoreceptor specific transcription factor NRL
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Prince, Eric
University of Colorado Anschutz Medical Campus, USA
Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in myc-driven medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Ramachandran, Cheppail
Miami Children's Hospital, USA
Inhibition of AKT signaling and tumor growth by supercritical CO2 extract of mango ginger (Curcuma amada Roxb.) in human glioblastoma cell line in vitro and in nude mice xenografts
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Ramaswamy, Vijay
Hospital for Sick Children, Canada
Posterior fossa ependymoma subgroups have distinct therapeutic and prognostic implications
Friday, May 8:  Session 8 - Ependymoma  -  8:20am - 9:00am
 

Remke, Marc
Hospital for Sick Children, Canada
Integrated genomics elucidates relative spatial homogeneity of embryonal brain tumors
Thursday, May 7:  Session 7 - Medulloblastoma 1  -  4:40pm - 5:10pm
 

Ritzmann, Tim
Children's Brain Tumour Research Centre, The University of Nottingham, UK
Heterogeneity of RelA protein expression in paediatric ependymoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Rodriguez, Fausto J.
Johns Hopkins University, USA
Notch signaling activation in pediatric low-grade astrocytoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Rood, Brian
Children's National Medical Center, USA
SILAC based quantitative proteomics of MYC-amplified medulloblastoma
Friday, May 8:  Session 10 - Medulloblastoma II, Part 2  -  10:30am - 11:20am
 

Rubens, Jeffrey
Johns Hopkins Hospital, USA
Targeting mTOR downstream of LIN28 in Atypical Teratoid Rhabdoid Tumors promotes apoptosis and suppresses tumorigenicity
Thursday, May 7:  Session 2 - ATRT  -  9:25am - 10:15am
 

Ruggieri, Rosamaria
The Feinstein Institute, USA
Pharmacological inhibition of MRK/ZAK kinase for the treatment of medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Ryall, Scott
Hospital for Sick Children, Canada
H3.3-K27M is a negative prognostic marker in thalamic pediatric glioma
Thursday, May 7:  Session 4 - High Grade Glioma  -  1:15pm - 2:25pm
 

Sabelstrom, Hanna
University of California, San Francisco, USA
SOX9 as a down-stream target in RAS/MEK-driven pediatric glioma
Thursday, May 7:  Session 3 - Brainstem Gliomas/High Grade Gliomas  -  10:35am - 12:05pm
 

Sahoo, Debashis
Department of Pediatrics, University of California San Diego School of Medicine, USA
Distinct brain lineage and stromal gene expression patterns in WNT, SHH, Group 3 and Group 4 molecular subgroups of pediatric medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Salloum, Ralph
Cincinnati Children's Hospital Medical Center, USA
A molecular biology and phase II study of Imetelstat (GRN163L) in children with recurrent or refractory central nervous system (CNS) malignancies: a Pediatric Brain Tumor Consortium Study 
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Saratsis, Amanda
Ann & Robert H. Lurie Children's Hospital of Chicago, USA
Tenascin-C: A novel therapeutic target in pediatric brainstem glioma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Schniederjan, Matthew J
Children's Healthcare of Atlanta, USA
High rate of concurrent BRAF-KIAA1549 gene fusion and 1p deletion in disseminated oligodendroglial-like leptomeningeal tumors
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Shahmanyan, David
City of Hope, USA
Neural stem cell-mediated enzyme/prodrug therapy for medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Sharma, Mehar
All India Institute of Medical Sciences, India
Role of mTOR signalling pathway in the pathogenesis of subependymal giant cell astrocytomas
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Singh, Rohini
University of Iowa, USA
Paradoxical genetic and epidemiologic relationships between cancer and autism
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Snuderl, Matija
NYU Langone Medical Center, USA
Novel candidate oncogenic drivers in pineoblastoma
Thursday, May 7:  Featured Poster Discussion: 5:30pm - 6:10pm
 

Suzuki, Mario
Department of Neurosurgery, Juntendo University School of Medicine, Japan
The Hippo pathway activity in AT/RT
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Tang, Yujie
Depts. of Neurology, Neurosurgery and Pediatrics, Stanford University, USA
Functionally-defined therapeutic targets in diffuse intrinsic pontine glioma
Thursday, May 7:  Session 3 - Brainstem Gliomas/High Grade Gliomas  -  10:35am - 12:05pm
 

Taylor, Isabella
Johns Hopkins Hospital, USA
LIN28 and MYC expressing pediatric glioblastomas are sensitive to inhibitors of glutamine metabolism
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Tech, Katherine
University of North Carolina at Chapel Hill, USA
Differential splicing of pyruvate kinase regulates progenitor cell cycle and medulloblastoma tumorigenesis
Friday, May 8:  Session 9 - Medulloblastoma II  -  9:00am - 10:10am
 

Teo, Wan-Yee
Humphrey Oei Institute of Cancer Research, National Cancer Center Singapore, Singapore
A bioinformatics evaluation of tumor-associated macrophages across 2 brain tumor types
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Valera, Elvis Terci
Faculdade de Medicina de Ribeirão Preto, USP., Brazil
The histone deacetylase inhibitor PCI-24781 shows antiproliferative, pro-apoptotic and radiosensitizing effects on pediatric glioblastoma cell-lines
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Veleta, Katherine
University of North Carolina at Chapel Hill, USA
Bcl-xL dependence of neural progenitors may be exploited to improve medulloblastoma therapy
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Venneti, Sriram
University of Michigan, USA
Detection of K27M mutant pediatric glioblastomas by immunohistochemistry
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Vinci, Mara
Institute of Cancer Research, UK
Functional diversity and co-operativity of subclonal populations of paediatric glioblastoma and diffuse intrinsic pontine glioma cells 
Thursday, May 7:  Session 1 - Featured Abstract Presentations  -  8:25am - 9:25am
 

Vitte, Jeremie
Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, USA
Conditional inactivation of Smarcb1 in P0 permissive mouse cells generates rhabdoid tumors in the peripheral nervous system and in the brain
Thursday, May 7:  Session 2 - ATRT  -  9:25am - 10:15am
 

Wang, Ange
Stanford University School of Medicine/Lucille Packard Children's Hospital, USA
Impact of molecular sub-type and craniospinal irradiation (CSI) dose on relapse of medulloblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Wang, Jun
Sanford-Burnham Medical Research Institute, USA
Genetically engineered mouse models of choroid plexus tumors
Thursday, May 7:  Session 6 - Germ Cell Tumors/Choroid Plexus Tumors  -  3:40pm - 4:40pm
 

Ward, Stacey
Washington University in St. Louis School of Medicine, USA
Co-inhibition of the Sonic hedgehog and CXCR4 pathways uniquely blocks tumor initiating cell function in medulloblastoma
Friday, May 8:  Session 10 - Medulloblastoma II, Part 2  -  10:30am - 11:20am
 

Xipell, Enric
University Hospital of Navarra, Spain
ER stress inducing drugs downregulates MGMT and MPG sensitizing pediatric glioma cell lines to TMZ
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Yamada, Shokei
Loma Linda University School of Medicine, USA
A role of spindle cells in glioblastoma growth
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Yao, Tsun-Wen
Departments of Pediatrics, UCSF, USA
Feedback activation of EGFR via PTPN9 leads to glioma escape from BRAFV600E targeted therapy
Thursday, May 7:  Session 5 - Low Grade Glioma  -  2:15pm - 3:15pm
 

Yegorov, Oleg
University of Florida, USA
Molecular engineering of amplified tumor RNA-pulsed dendritic cells in adoptive cellular therapy targeting medulloblastoma and glioblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Yu, Kwanha
Baylor College of Medicine, USA
Decoding the cellular heterogeneity of pediatric high grade glioma
Thursday, May 7:  Session 3 - Brainstem Gliomas/High Grade Gliomas  -  10:35am - 12:05pm
 

Zhang, Zhiguo
Mayo Clinic, USA
Impact of H3.3K27M mutation on cancer epigenome
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm
 

Zhao, Haotian
Sanford Research, USA
Notch and Shh signaling pathways converge on the primary cilium to promote choroid plexus tumor initiation from epithelial progenitors
Thursday, May 7:  Session 6 - Germ Cell Tumors/Choroid Plexus Tumors  -  3:40pm - 4:40pm
 

Zhu, Wenyi
Baylor College of Medicine, USA
Daam2 promotes tumor proliferation and migration in glioblastoma
Thursday, May 7:  Poster Reception  -  5:30pm - 7:30pm