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Session 10 - Medulloblastoma II, Part 2
Friday, May 8, 10:30am - 11:20am

MODERATORS: Richard Grundy, Anna Kenney

 


MB-24 SILAC based quantitative proteomics of MYC-amplified medulloblastoma
Jerome Staal, Ling San Lau, Huizhen Zhang, Yetrib Hathout, Kristy Brown, Brian Rood*
Children's National Medical Center, USA
MB-36 WIP1 augments sonic hedgehog (SHH) signaling and is a target in SHH medulloblastomas
Juhyun Lee1, Meghan Buss1, Jing Wen1, Marc Remke3,4, Michael Taylor3,4, Robert Castellino*2,1
1Emory University, USA, 2Aflac Cancer and Blood Disorders Center, USA, 3University of Toronto, Canada, 4The Hospital for Sick Children, Canada
MB-02 Sonic hedgehog induces YB-1 in a YAP-dependent manner to regulate Igf2 expression and proliferation in cerebellar granule neuron progenitors and medulloblastoma cells
Abhinav Dey*1, Mélanie Robitaille2, Marc Remke3, Caroline Maier1, Anshu Malhotra1, Alex Gregorieff4, Jeffrey Wrana4, Michael Taylor3, Stéphane Angers2, Anna Kenney1
1Emory University, USA, 2University of Toronto, Canada, 3Hospital for Sick Children, Canada, 4Mount Sinai Hospital, Canada
MB-23 Co-inhibition of the Sonic hedgehog and CXCR4 pathways uniquely blocks tumor initiating cell function in medulloblastoma
Stacey Ward*, Joshua Rubin
Washington University in St. Louis School of Medicine, USA
MB-25 Regulation of medulloblastoma formation by Gfi1 and Gfi1b
Catherine Lee*1,2, Paul Northcott3, Thomas Zichner4, Jan Korbel4, Stefan Pfister3, Robert Wechsler-Reya1
1Sanford Burnham Medical Research Institute (SBMRI), USA, 2University of California, San Diego (UCSD), USA, 3German Cancer Research Center (DKFZ), Germany, 4European Molecular Biology Laboratory (EMBL), Germany